LGR5, also named as GPR49, GPR67 and HG38, belongs to the G-protein coupled receptor 1 family. It is an orphan receptor. LGR5 is a stem cell marker of the intestinal epithelium and the hair follicule. It is a target gene of Wnt signaling.
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Human LHB knockout HeLa cell 108010045030 monoclonal antibodies Proteins 0.000 claims description 9 2014-11-19, Genentech Inc, Anticuerpos anti-lgr5 e inmunoconjugados. LGR5 promotes tumorigenicity and invasion of glioblastoma stem-like cells and is a potential therapeutic target for a subset of glioblastoma patients2019Ingår i: Human GPR49 / LGR5 Protein (Over-Expression Lysate Myc + DDK) · Human AGPAT9 / MAG1 Protein Antibodies · Assays · (Cell) Culture · Chemicals. from 101 clinically healthy individuals using multiplexed antibody assays. leads to increased Wnt activity, elevated LGR5 levels and enrichment of gene 13 nov. 2017 — f 1938. Studies on some factors regulating antibody synthesis Stem cells and development: studies on SUFU and LGR5.
Dilution : WB~~1:1000 IF~~1:100 FC~~1:25: Format : Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. Lgr5/GPR49 in HEK293 Human Cell Line Transfected with Mouse Lgr5/GPR49. Lgr5/GPR49 was detected in immersion fixed HEK293 human embryonic kidney cell line transfected with GFP (green) tagged mouse LGR5 using Mouse Anti-Human Lgr5/GPR49 Monoclonal Antibody (Catalog # MAB8078) at 10 µg/mL for 3 hours at room temperature.
13 dec. 2017 — Mouse monoclonal EB1 antibody, BD Bioscience, 610535, primary antibody 1:200. Rabbit anti-Lgr5 antibody, Abgent, AP2745d, primary
innovative, full-length multispecific antibodies (Biclonics® and Triclonics™), antibody targeting EGFR and LGR5, in metastatic colorectal cancer (CRC). Green: Anti-Smad2 antibody. [EP784Y] (ab40855) observed at 58 kDa.
Buy rabbit polyclonal antibody to LGR5 (A894). Validated Applications: WB and ICC. Reactivity: Human and Mouse. ✔️ 100% Guarantee ✔️ FREE Shipping.
Cited in 2 reference(s). LGR5 (GPR49 or GPR67) antibody labeling of mouse colon. LGR5 proteins decorate the intestinal stem cells in the mouse colon. Note the lineage development from an intestinal stem cell (arrow). Anti-LGR5 (GPR49) Antibody from rabbit, purified by affinity chromatography; Synonym: Leucine-rich repeat-containing G-protein coupled receptor 5, G-protein coupled receptor 49, G-protein coupled receptor 67, G-protein coupled receptor HG38; find Sigma-Aldrich-ABD17 MSDS, related peer-reviewed papers, technical documents, similar products & more at Sigma-Aldrich. 2020-12-19 · GPR49 Antibody, G-protein coupled receptor 67 Antibody, G-protein coupled receptor HG38 Antibody, Leucine-rich repeat-containing G-protein coupled receptor 5 Antibody, LGR5 Antibody, G-protein coupled receptor 49 Antibody, GPR67 Antibody, GPCR GPR49 antibody Specifications for LGR5 Antibody, anti-mouse Overview Clone DA04-10E8.9 recognizes the mouse LGR5 antigen, also known as leucine-rich-repeat-containing G-protein–coupled receptor 5 or Gpr49 but not with its close homologues LGR4 or LGR6. 2020-05-28 · This is a Validated Antibody Database (VAD) review about human LGR5, based on 20 published articles (read how Labome selects the articles), using LGR5 antibody in all methods.
Anti-LGR5 Antibody Products Anti-LGR5 antibodies are offered by a number of suppliers. This target gene encodes the protein 'leucine rich repeat containing G protein-coupled receptor 5' in humans and may also be known as FEX, GRP49, GPR49, GPR67, G-protein coupled receptor 49, and G-protein coupled receptor 67. Search results for lgr5 antibody at Sigma-Aldrich. Compare Products: Select up to 4 products. *Please select more than one item to compare
Anti-LGR5 antibody (ab75732) is not available Anti-LGR5 antibody ( ab219107 ) or Anti-LGR5 antibody [EPR3065Y] ( ab75850 ) are our recommended alternatives. You can still access the archived datasheet PDF below
Specifications for LGR5 Antibody, anti-human Overview Clone DA03-22H2.8 reacts with the human leucine-rich repeat-containing G-protein–coupled receptor 5 (LGR5) but not with its close homologues LGR4 or LGR6.
Validated in WB, ICC/IF, IHC-P. Tested in Human, Mouse. Buy anti-LGR5 antibody, anti-Human, Mouse LGR5 Polyclonal Antibody- NP_001264155.1 (MBS856950) product datasheet at MyBioSource, Primary Antibodies Rabbit polyclonal LGR5 Antibody validated in IHC to detect human small intestine, colon, colon cancer, liver cancer tissues. Referenced in 3 publications.
Anti-LGR5 antibody (ab75732) is not available Anti-LGR5 antibody ( ab219107 ) or Anti-LGR5 antibody [EPR3065Y] ( ab75850 ) are our recommended alternatives. You can …
LGR5-Targeted Antibody-Drug Conjugate Eradicates Gastrointestinal Tumors and Prevents Recurrence.
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Spectraviewer. Rabbit anti LGR5 antibody recognizes Leucine-rich repeat-containing G-protein coupled receptor 5 (LGR5), also known as G-protein coupled receptor 49, G-protein coupled receptor 67 and G-protein coupled receptor HG38.
To 12 Nov 2019 Conclusion: LGR5 expression was higher in colorectal cancer than in colon cancer tissue sections was optimized for the LGR5 antibody. Leucine-rich repeat-containing G-protein coupled receptor 5 (LGR5) also known as G-protein coupled receptor 49 (GPR49) or G-protein coupled receptor 67 anti-LGR5 Antibody reacting with Rabbit and identified with ELISA, IHC, IF. Quality is guaranteed.
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LGR5 Antibody (MA5-25644) in WB Western blot analysis of LGR5 in HEK293T cells in untransfected (Left lane) and transfected (Right lane) samples using 5 µg per lane. The samples were separated by SDS-PAGE and probed with LGR5 (Product # MA5-25644) monoclonal antibody.
This antibody has been referred to as "RD20" by Peng et al.(1). Anti-LGR5 Antibody Products Anti-LGR5 antibodies are offered by a number of suppliers. This target gene encodes the protein 'leucine rich repeat containing G protein-coupled receptor 5' in humans and may also be known as FEX, GRP49, GPR49, GPR67, G-protein coupled receptor 49, and G-protein coupled receptor 67.
Fig.1 LGR5 promotes Wnt/β-catenin signaling. (Morgan, 2018) Published Data Anit-LGR5 antibody and its ADC format inhibit tumor growth and recurrence in vivo. (Gong, 2016) Inhibition of LGR5 with AZD8931 (AZD) significantly blocked EC CM-induced colorectal tumor growth.
Se hela listan på sigmaaldrich.com Antibody Testing Data (3) FIGURE 1/3 LGR5 Antibody (PA5-87974) in WB Western Blot analysis of LGR5 in extracts of various cell lines using LGR5 Polyclonal Antibody (Product # PA5-87974) at a dilution of 1:1000. LGR5 Antibody (PA5-85920) in WB. Western blot analysis of LGR5 in different lysates using a Polyclonal antibody (Product #PA5-85920) at a dilution of 1:1000. Positive control: Lane 1: F9, Lane 2: Hela, Lane 3: K562. Mouse monoclonal LGR5 antibody [OTI2A2].
Store at -20°C as received. Rabbit Polyclonal LGR5 antibody. Validated in WB, ICC/IF, IHC-P.